Patent Number: 8,722,133

Title: Method for production of orally rapidly disintegrating tablet comprising imidafenacin as active ingredient

Abstract: The present invention herein provides an imidafenacin-containing orally rapidly disintegrating tablet which is excellent in the photostability. The present invention comprises the steps of: (A) granulating imidafenacin together with starch to thus give a granulated product having an imidafenacin concentration ranging from 0.001 to 3% by mass and a starch concentration ranging from 40 to 99.999% by mass; (B) covering the granulated product prepared in the step (A) with a non-cellulosic coating agent; and (C) blending the granulated product obtained in the preceding step (B) with an excipient and a disintegrating agent and then forming the resulting mixture into a tablet according to the compression molding technique.

Inventors: Ishizaki; Toshihiro (Shimotsuga-gun, JP), Aoki; Yoshinobu (Shimotsuga-gun, JP)

Assignee: Kyorin Pharmaceutical Co., Ltd.

International Classification: A61K 9/20 (20060101); A61K 9/26 (20060101); A61K 9/28 (20060101)

Expiration Date: 5/13/12018