Patent Number: 8,722,381

Title: Variants of a Bacillus strearothermophilus alpha-amylase and uses thereof

Abstract: Described are variants of alpha (.alpha.)-amylases having altered starch hydrolysis profiles. The variants have improved thermostability and increased specific activity, resulting in reduced peak viscosity and altered final viscosity during starch liquefaction. The amylase variants are useful, e.g., in liquefaction and other starch degradation processes.

Inventors: Ramer; Sandra W. (Sunnyvale, CA), Pepsin; Michael J. (Castro Valley, CA), Shaw; Andrew (San Francisco, CA)

Assignee: Danisco US Inc.

International Classification: C12N 9/28 (20060101); C12P 19/14 (20060101); A61K 9/68 (20060101); C07H 21/04 (20060101); C12P 7/14 (20060101); C12P 7/08 (20060101); C12P 7/06 (20060101); C12P 19/04 (20060101)

Expiration Date: 5/13/12018