Patent Number: 8,722,661

Title: Pyrrolopyrimidone and pyrrolopyridone inhibitors of tankyrase

Abstract: There are provided compounds of the formula (I) ##STR00001## wherein Q, R.sub.1 and R.sub.2 are defined herein. The compounds have activity as anticancer agents.

Inventors: Haynes; Nancy-Ellen (Cranford, NJ), Hermann; Johannes (Jersey City, NJ), Kim; Kyungjin (Livingston, NJ), Scott; Nathan Robert (Livingston, NJ), Yi; Lin (Basking Ridge, NJ), Zak; Mark (San Mateo, CA)

Assignee: Hoffmann-La Roche Inc.

International Classification: A61K 31/00 (20060101); C07D 401/00 (20060101); C07D 487/00 (20060101); C07D 471/02 (20060101)

Expiration Date: 5/13/12018