Patent Number: 8,722,686

Title: Hydroxamic acid derivatives useful as antibacterial agents

Abstract: The invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof, thereof, wherein: G is a group of formula (II); and pharmaceutically acceptable salts, prodrugs, hydrates, or solvates, thereof, wherein A, B. L.sup.1-L.sup.4 A, B, R.sup.1-R.sup.4 and m are as defined herein. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and their use in treating a bacterial infection.

Inventors: Brown; Matthew F. (Groton, CT), Donovan; Charles F. (Colchester, CT), Ellsworth; Edmund L. (Kalamazoo, MI), Hoyer; Denton W. (Niantic, CT), Johnson; Timothy A. (Richland, MI), Lall; Manjinder S. (Groton, CT), Lim-Berakis; Chris (Groton, CT), Murphy; Sean T. (San Diego, CA), Sherry; Debra A. (Chelsea, MI), Taylor; Clarke B. (Ann Arbor, MI), Warmus; Joseph S. (Groton, CT)

Assignee: Pfizer Inc.

International Classification: A61K 31/70 (20060101); A61K 31/415 (20060101); A61K 31/535 (20060101); C07D 239/42 (20060101); A61K 31/67 (20060101); C07D 235/02 (20060101); C07D 307/02 (20060101); C07D 233/54 (20060101); C07D 403/02 (20060101); C07D 261/06 (20060101); C07D 277/30 (20060101); C07D 213/56 (20060101); C07D 491/02 (20060101); C07D 239/02 (20060101); C07D 413/02 (20060101); A61K 31/165 (20060101)

Expiration Date: 5/13/12018