Patent Number: 8,791,138

Title: Compositions and methods for alleviating depression or improving cognition

Abstract: This application describes compositions of receptor inhibitors, including antipsychotic agents, for example haloperidol, and methods of use for alleviating clinical depression, improving cognition and/or treating other syndromes, conditions or diseases for which anti-depressant agents are prescribed. Furthermore, this application describes compositions and methods to induce supersensitivity in dopamine D2 and other receptors involved in depression and/or cognition as a means of alleviating clinical depression or improving cognition.

Inventors: Seeman; Philip (Toronto, CA), Tokeikis; Philip M. (Vancouver, CA)

Assignee: Clera Inc.

International Classification: A01N 43/40 (20060101); A61K 31/445 (20060101)

Expiration Date: 7/29/12018