Patent Number: 8,791,152

Title: Stable pharmaceutical composition containing docetaxel and a method of manufacturing the same

Abstract: The present invention relates to a stable pharmaceutical composition for injection containing docetaxel and a method of preparing the same. More particularly, the present invention relates to a pharmaceutical composition for injection containing docetaxel having better storage stability than conventional medications, which is prepared by dissolving docetaxel, a water-insoluble compound, in distilled water after mixing it with cyclodextrin (CD) and a water-soluble polymer such as hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) and lyophilizing the mixture, and a method of preparing the same.

Inventors: Kim; Nam Ho (Seongnam-si, KR), Lee; Jin Young (Suwon-si, KR), Kim; Jae-Sun (Suwon-si, KR), Lee; Nam Kyu (Suwon-si, KR), Jang; Woo Jae (Gunpo-si, KR), Oh; Joon Gyo (Suwon-si, KR), Lee; Yoon-Jung (Yongin-si, KR), Kim; Woong Sik (Suwon-si, KR), Sung; Jin-Heung (Bucheon-si, KR), Um; Key An (Suwon-si, KR)

Assignee: SK Chemicals Co., Ltd.

International Classification: A61K 31/335 (20060101)

Expiration Date: 7/29/12018