Patent Number: 8,796,003

Title: Label free kinase assays and reagents

Abstract: This disclosure describes methods and compositions for measuring the binding specificity, kinetics and affinity of kinase inhibitors indirectly using mass sensing analytical techniques, such as SPR, through the competitive displacement of detectable signal-inducing kinase binding molecule. Further provided are methods for preparing such molecules.

Inventors: Dudek; Ronald P. (Sammamish, WA), Cicirelli; Michael (Kirkland, WA), Parker; Timothy C. (Bothwell, WA)

Assignee: Plexera, LLC

International Classification: C12N 9/12 (20060101); C40B 30/04 (20060101); C40B 40/10 (20060101)

Expiration Date: 8/05/12018