Patent Number: 8,796,266

Title: Cyclothiocarbamate derivatives as progesterone receptor modulators

Abstract: Methods of using compounds which are progesterone receptor agonists for contraception and the treatment of progesterone-related maladies alone or in combination with an estrogen receptor agonist or progesterone receptor antagonist are provided. These compounds have the structure: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and Q.sup.1 are defined herein.

Inventors: Zhang; Puwen (Audubon, PA), Fensome; Andrew (Stow, MA), Terefenko; Eugene A. (Center Valley, PA), Zhi; Lin (La Jolla, CA), Jones; Todd K. (San Diego, CA), Edwards; James P. (San Diego, CA), Tegley; Christopher M. (Thousand Oaks, CA), Wrobel; Jay E. (Lawrenceville, NJ), Collins; Mark A. (Collegeville, PA)

Assignee: Wyeth LLC

International Classification: A61K 31/535 (20060101)

Expiration Date: 8/05/12018