Patent Number: 8,796,447

Title: Process for producing benzo[B][1,4]diazepine-2,4-dione compound

Abstract: A process for producing a compound represented by formula (1), ##STR00001## wherein each of R.sup.1, R.sup.2, R.sup.3 and R.sup.4, which may be the same or different, represents a hydrogen atom or a lower alkyl group, the process includes deprotecting a protective group (R.sup.5) of a compound represented by formula (2), ##STR00002## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined above, and R.sup.5 represents a protective group of a hydroxy group. The process is an industrially advantageous, simple, and efficient process for producing a key intermediate of a benzo[b][1,4]diazepine-2,4-dione compound, which is a therapeutic medicine for arrhythmia.

Inventors: Tsujimori; Hisayuki (Osaka, JP), Taira; Shinichi (Osaka, JP), Yukawa; Hirotaka (Osaka, JP), Abe; Kaoru (Osaka, JP)

Assignee: Otsuka Pharmaceutical Co., Ltd.

International Classification: C07D 243/12 (20060101)

Expiration Date: 8/05/12018