Patent Number: 8,796,448

Title: Compounds, compositions, and methods for treating Alzheimer's disease

Abstract: Novel methods and compounds for treating Alzheimer's Disease are provided. In one aspect, the invention provides methods for treating Alzheimer's Disease by administering certain phenothiazine derivatives. In one embodiment, the methods include administering an effective amount of a 3-oxo-7-dialkyl-amino-phenothiazine derivative, or 3-oxo-7-dialkyl-amino-phenothiazine. In another embodiment, the invention provides methods for treating Alzheimer's Disease by administering an effective amount of a 3,7-diazetidin-1-yl-phenothiazine or a derivative thereof. In another aspect, the invention provides novel azetidinyl phenothiazine compounds.

Inventors: Lingappa; Vishwanath (San Francisco, CA), Hurt; Clarence R. (Los Altos, CA)

Assignee: Prosetta Antiviral Inc.

International Classification: C07D 417/14 (20060101)

Expiration Date: 8/05/12018