Patent Number: 8,815,550

Title: Targeted perhydrolases

Abstract: Disclosed herein are compositions and methods to target enzymatic peracid production to a target surface. The peracid benefit agent produced by the targeted perhydrolytic enzyme can be use for a variety of applications such as bleaching, whitening, disinfecting, destaining, deodorizing, and combinations thereof. Specifically, a fusion protein comprising a perhydrolytic enzyme and at least one peptidic component having affinity for a target surface (excluding body surfaces and oral care surfaces) is used in combination with a suitable substrate and a source of peroxygen to enzymatically produce a peracid on or near the surface of the target material. In a preferred aspect, the target surface is a cellulosic material.

Inventors: DiCosimo; Robert (Chadds Ford, PA), Cunningham; Scott D (Chadds Ford, PA), Fahnestock; Stephen R (Wilmington, DE), Gruber; Tanja Maria (Media, PA), Payne; Mark S (Wilmington, DE), Rouviere; Pierre E (Wilmington, DE), Solomon; Linda Jane (Wilmington, DE), Wang; Hong (Kennett Square, PA)

Assignee: E I du Pont de Nemours and Company

International Classification: C12P 7/40 (20060101); C12N 9/96 (20060101); C12N 9/18 (20060101)

Expiration Date: 8/26/12018