Patent Number: 8,815,778

Title: PH modulation method to detect ligand-receptor binding

Abstract: The present disclosure relates to detecting receptor-ligand binding by measuring local pH modulation using a pH-sensitive fluorophore.

Inventors: Jung; Hyunsook (Daejon, KR), Robison; Aaron D (Bryan, TX), Cremer; Paul S. (College Station, TX)

Assignee: The Texas A&M University System

International Classification: G01N 21/64 (20060101); C07D 471/06 (20060101)

Expiration Date: 8/26/12018