Patent Number: 8,815,942

Title: Combination therapy and uses thereof for treatment and prevention of parasitic infection and disease

Abstract: The invention relates to compounds, methods, uses, compositions, combinations, kits and packages for the prevention and/or treatment of parasite infection (e.g., Plasmodium parasites) and/or disease (e.g., malaria) based on uses of (a) cystamine, cysteamine, and analogs, derivatives, prodrugs, precursors thereof; an agent capable of inducing their production; and/or salts thereof, and (b) artemisinin and functional derivative, analog, conjugate, metabolite, prodrug or precursor thereof, and/or salts thereof.

Inventors: Gros; Philippe (St-Lambert, CA), Min-Oo; Gundula (San Francisco, CA), Fortin; Anny (Montreal, CA)

Assignee: The Royal Institution for the Advancement of Learning/McGill University

International Classification: A61K 31/365 (20060101); A61K 31/145 (20060101)

Expiration Date: 8/26/12018