Patent Number: 8,816,082

Title: Heterocyclyl-pyridinyl-based biphosphonic acid, pharmaceutically acceptable salt thereof, composition thereof and method of use thereof

Abstract: The present invention relates to novel compounds, compositions containing same and methods for inhibiting human farnesyl pyrophosphate synthase or for the treatment or prevention of disease conditions using said compounds; ##STR00001##

Inventors: Tsantrizos; Youla S. (Montreal, CA), De Schutter; Joris Wim (Montreal, CA), Lin; Yih-Shyan (Montreal, CA)

Assignee: The Royal Institution for the Advancement of Learning/McGill University

International Classification: C07F 9/6558 (20060101); A61P 19/10 (20060101); C07F 9/58 (20060101); A61P 35/00 (20060101); A61P 31/12 (20060101); A61P 3/06 (20060101); A61K 31/675 (20060101)

Expiration Date: 8/26/12018