Patent Number: 8,822,413

Title: Bifunctional hormone having alpha-MSH activity and natriuretic peptide activity and uses thereof

Abstract: A bifunctional hormone exhibiting an alpha-MSH activity and a natriuretic peptide activity is described. The bifunctional hormone comprises for example a first domain having alpha-MSH related hormonal activity covalently linked to a second domain having natriuretic peptide related hormonal activity. The bifunctional hormone of the present invention is useful for example for the prevention and/or treatment of renal related diseases or conditions, such as acute renal failure (ARF) or acute kidney injury (AKI).

Inventors: Peri; Krishna G. (Montreal, CA), Habi; Abdelkrim (Pierrefonds, CA)

Assignee: Theratechnologies Inc.

International Classification: A61K 38/22 (20060101); A61K 38/16 (20060101); A61K 38/00 (20060101)

Expiration Date: 9/02/12018