Patent Number: 8,822,500

Title: Tyrosine kinase inhibitors

Abstract: The present disclosure relates to the field of tyrosine kinase enzyme inhibition, in particular anaplastic lymphoma kinase (ALK) inhibition using novel small molecules. Provided are compounds capable to modulate ALK activity, compositions that comprise the compounds, and methods of using the compounds for the treatment or prevention of diseases or conditions that are characterized by ALK activity or expression.

Inventors: Gregor; Vlad Edward (Del Mar, CA)

Assignee: Chembridge Corporation

International Classification: A61K 31/4439 (20060101); C07D 401/12 (20060101)

Expiration Date: 9/02/12018