Patent Number: 8,822,532

Title: Bis[thiohydrazide amide] compounds for treating leukemia

Abstract: Certain bis[thio-hydrazide amide]-related compounds are found to be surprisingly effective at treating with leukemia, e.g., acute myeloid leukemia (AML). Methods of treating a subject with AML including administering bis[thio-hydrazide amide]-related compounds described herein, are disclosed.

Inventors: Nagai; Masazumi (Lexington, MA), Shen; Jianhua (Andover, MA)

Assignee: Synta Pharmaceuticals Corp.

International Classification: A61K 31/28 (20060101); A61P 35/02 (20060101); A61K 31/315 (20060101)

Expiration Date: 9/02/12018