Patent Number: 8,822,681

Title: Azaindoles useful as inhibitors of janus kinases

Abstract: The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

Inventors: Farmer; Luc (Montreal, CA), Martinez-Botella; Gabriel (West Roxbury, MA), Pierce; Albert (Cambridge, MA), Salituro; Francesco (Marlborough, MA), Wang; Jian (Newton, MA), Wannamaker; Marion W. (Stow, MA), Wang; Tiansheng (Concord, MA)

Assignee: Vertex Pharmaceuticals Incorporated

International Classification: C07D 403/00 (20060101)

Expiration Date: 9/02/12018