Patent Number: 8,822,692

Title: Diterpenoid derivatives endowed of biological properties

Abstract: The present invention relates to new diterpenoid derivatives of formula (I), processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, urinary incontinence, asthma, or Alzheimer's disease and/or to prevent obstructive vascular lesions consequently to arteriotomy and/or angioplasty, and to prevent organ damage in hypertensive patients.

Inventors: Cerri; Alberto (Milan, IT), Gobbini; Mauro (Mercallo, IT), Torri; Marco (Rho, IT), Ferrari; Patrizia (Varese, IT), Ferrandi; Mara (Milan, IT), Bianchi; Giuseppe (Milan, IT)

Assignee: Sigma-Tau Industrie Farmaceutiche Riunite, S.p.A.

International Classification: C07D 211/46 (20060101); C07D 207/12 (20060101); C07C 251/58 (20060101); C07C 249/04 (20060101); C07C 277/00 (20060101); C07C 279/12 (20060101); A61K 31/445 (20060101)

Expiration Date: 9/02/12018