Patent Number: 8,822,727

Title: Processes for the preparation of intermediates related to the 5-HT.sub.2C agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Abstract: The present invention provides processes and intermediates useful in the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, a serotonin (5-HT) receptor agonist that is useful in the treatment or prophylaxis of, for example, central nervous system disorders, such as obesity.

Inventors: Carlos; Marlon V. (Chula Vista, CA), Castro; Ryan O. (San Diego, CA), Gharbaoui; Tawfik (Escondido, CA), Lu; Xiao-Xiong (San Diego, CA), Ma; You-An (Poway, CA), San Martin; Nicholas D. (San Diego, CA)

Assignee: Arena Pharmaceuticals, Inc.

International Classification: C07C 211/00 (20060101)

Expiration Date: 9/02/12018