Patent Number: 8,871,708

Title: Compositions and methods for treating AIDS or cancer by inhibiting the secretion of microparticles

Abstract: Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.

Inventors: Bond; Vincent Craig (Stone Mountain, GA), Powell; Michael (Douglassville, GA), Huang; Ming Bo (Atlanta, GA), Ali; Syed (Atlanta, GA), Raymond; Andrea D. (Atlanta, GA), Shelton; Martin Neville (Stone Mountain, GA), Villinger; Francois Jean (Decatur, GA)

Assignee:

International Classification: A61P 31/12 (20060101); A61P 31/18 (20060101); A61K 39/21 (20060101); A61K 39/00 (20060101); A61P 35/00 (20060101); C12N 5/22 (20060101)

Expiration Date: 2018-10-28 0:00:00