Patent Number: 8,871,735

Title: Methods and compositions for providing cardiac protection

Abstract: The invention provides a method of reducing infarct size and/or limiting, decreasing and/or inhibiting reperfusion injury and/or ameliorating heart failure in a patient comprising administering a pharmaceutically effective amount of at least one compound capable of inhibiting AC5 to the patient. The compound capable of inhibiting AC5 is particularly effective when administered during or after reperfusion in patients suffering from an ischemic injury.

Inventors: Vatner; Stephen F. (New York, NY), Vatner; Dorothy E. (New York, NY)

Assignee: Rutgers, The State University of New Jersey

International Classification: A01N 43/04 (20060101); A61K 31/70 (20060101)

Expiration Date: 2018-10-28 0:00:00