Patent Number: 8,871,765

Title: Substituted 4-(4-fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one derivatives as poly (ADP-ribose) polymerase-1 inhibitors

Abstract: Disclosed are compounds of general formula (I), their stereoisomers, regioisomers, tautomeric forms and novel intermediates involved in their synthesis, their pharmaceutically acceptable salts. These compounds are suitable as Poly(ADP-ribose)polymerase-1 inhibitors (PARP-1 inhibitors). ##STR00001##

Inventors: Shrivastava; Brijesh Kumar (Gujarat, IN)

Assignee: Cadila Healthcare Limited

International Classification: A61K 31/502 (20060101); C07D 237/32 (20060101)

Expiration Date: 2018-10-28 0:00:00