Patent Number: 8,871,775

Title: Compounds

Abstract: Pyrimidone compounds of formula (I): ##STR00001## are inhibitors of the enzyme Lp-PLA.sub.2 and are of use in treating atherosclerosis.

Inventors: Hickey; Deirdre Mary Bernadette (Essex, GB), Ife; Robert John (Essex, GB), Leach; Colin Andrew (Essex, GB), Pinto; Ivan Leo (Essex, GB), Smith; Stephen Allan (Essex, GB), Stanway; Steven James (Essex, GB)

Assignee: Glaxo Group Limited

International Classification: A61K 31/519 (20060101); C07D 473/00 (20060101); C07D 239/02 (20060101)

Expiration Date: 2018-10-28 0:00:00