Patent Number: 8,871,802

Title: Naphthoquinones for disease therapies

Abstract: The present invention discloses novel naphtho[2,3-b]furan-4,9-diones and naphtho[2,3-b]thiophene-4,9-diones and methods of making and using the same. The present invention also discloses pharmaceutical compositions comprising novel naphtho[2,3-b]furan-4,9-dione or naphtho[2,3-b]thiophene-4,9-diones for the treatment of various indications including proliferative diseases.

Inventors: Jiang; Zhiwei (Stow, MA), Wang; Aijin (West Roxbury, MA), Li; Xian (Fengcheng, CN), Li; Qingrong (FuYu Town, CN), Hu; Hongwei (Suifenhe, CN), Xu; Jiali (Tongcheng, CN), Hu; Yuesong (Zhoushan, CN), Ye; Yan (Zhoushan, CN)

Assignee: Zhoushan HaiZhongZhou Xinsheng Pharmaceuticals Co., Ltd.

International Classification: A61K 31/343 (20060101); C07D 307/92 (20060101)

Expiration Date: 2018-10-28 0:00:00