Patent Number: 8,877,164

Title: Pharmaceutical aerosol formulations for pressurized metered dose inhalers comprising a sequestering agent

Abstract: Aerosol solution formulation for use in an aerosol inhaler which includes at least one active ingredient selected from 20-ketosteroids and quinolinone derivatives, a propellant containing a hydrofluoroalkane, a cosolvent, and a specific amount of a sequestering agent that stabilizes the formulation. By way of example, the stabilizing agent may be phosphoric acid or sulphuric acid.

Inventors: Lewis; David Andrew (Wilts, GB), Meakin; Brian John (Bath, GB), Delcanale; Maurizio (Parma, IT), Pivetti; Fausto (Sala Baganta, IT)

Assignee: Chiesi Farmaceutici S.p.A.

International Classification: A61K 31/573 (20060101); A61K 47/04 (20060101); A61K 9/72 (20060101); A61K 9/12 (20060101); A61K 47/02 (20060101)

Expiration Date: 2019-11-04 0:00:00