Patent Number: 8,877,193

Title: Transdiscal administration of anti-TNF.alpha. antibodies and growth differentiation factors

Abstract: The present invention relates to injecting a high specificity cytokine antagonist into a diseased intervertebral disc.

Inventors: Serhan; Hassan (South Easton, MA), Attawia; Mohamed (Holmdell, NJ), DiMauro; Thomas M. (Southboro, MA), Kadiyala; Sudhakar (Newton, MA), Urbahns; David (Barrington, RI), Bruder; Scott (Franklin Lakes, NJ)

Assignee: DePuy Synthes Products, LLC.

International Classification: A61K 39/00 (20060101); A61K 39/395 (20060101)

Expiration Date: 2019-11-04 0:00:00