Patent Number: 8,877,491

Title: Polynucleotides encoding humanized anti-NGF antibodies

Abstract: Method for the humanization of the VH and VL variable regions of an animal antibody of known sequence, humanized animal antibody obtainable according to the method, in particular anti-NGF and anti-TrkA humanized animal antibodies.

Inventors: Cattaneo; Antonino (Rome, IT), Lamba; Doriano (Rome, IT), Covaceuszach; Sonia (Rome, IT)

Assignee: Abbvie Inc.

International Classification: C07K 16/22 (20060101); C12N 15/85 (20060101)

Expiration Date: 2019-11-04 0:00:00