Patent Number: 8,877,517

Title: Methods for ionophorically screening pore forming bacterial protein toxins and receptors

Abstract: A method for determining the amount of pore forming bacterial toxin protein in a sample is provided, the method including the steps of a) forming a membrane comprising a lipid bilayer and a receptor, b) contacting the membrane with an ion solution and the sample, c) measuring ion flow through the membrane, d) comparing the ion flow through the membrane to a standard curve, and e) determining the amount of pore forming bacterial toxin protein in the sample.

Inventors: Cuppoletti; John (Cincinnati, OH)

Assignee:

International Classification: C12M 1/00 (20060101); C12M 1/34 (20060101); G01N 33/543 (20060101)

Expiration Date: 2019-11-04 0:00:00