Patent Number: 8,877,714

Title: Compositions comprising receptor-associated protein (RAP) variants specific for LRP2 and uses thereof

Abstract: The present invention relates generally to receptor-selective variants of the low-density lipoprotein receptor-associated protein (RAP) and compositions thereof, methods of generating such variants and methods of using such receptor-selective RAP variant compositions for therapeutic purposes. The invention also relates to antibodies that bind to one or a small subset of CR-containing proteins.

Inventors: Starr; Christopher M. (Sonoma, CA), Zankel; Todd C. (San Francisco, CA)

Assignee: Raptor Pharmaceutical Inc.

International Classification: C07K 14/705 (20060101); A61K 38/17 (20060101)

Expiration Date: 2019-11-04 0:00:00