Patent Number: 8,877,778

Title: Benzofurane compounds

Abstract: The present invention is concerned with novel dual modulators of the 5-HT.sub.2A and D.sub.3 receptors of formula (I) ##STR00001## wherein n, x, Y, R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as pharmaceuticals.

Inventors: Rodriguez Sarmiento; Rosa Maria (Basel, CH), Wichmann; Juergen (Steinen, DE)

Assignee: Hoffmann-La Roche Inc.

International Classification: A61K 31/445 (20060101); C07D 405/14 (20060101)

Expiration Date: 2019-11-04 0:00:00