Patent Number: 8,877,800

Title: Kappa-opiate agonists for the treatment of diarrhea-predominant irritable bowel syndrome

Abstract: The present invention concerns methods useful in treating a subject having diarrhea-predominant IBS (IBS-D) by administering N-methyl-N-[(1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidin-1-yl)ethyl]-2,2-dip- henylacetamide and/or a pharmaceutically acceptable salt thereof to the subject.

Inventors: Mangel; Allen (Chapel Hill, NC)

Assignee: Tioga Pharmaceuticals, Inc.

International Classification: A61K 31/40 (20060101)

Expiration Date: 2019-11-04 0:00:00