Patent Number: 8,877,814

Title: Titration package for neramexane and its use in the treatment of an inner ear disorder

Abstract: The present invention relates to a titration scheme for the administration of a 1-amino-alkylcyclohexane derivative which allows for quick attainment of an effective dose of a 1-amino-alkylcyclohexane derivative while minimizing side effects. The present invention further relates to a titration package for providing a 1-amino-alkylcyclohexane derivative (e.g., neramexane or a pharmaceutically acceptable salt thereof) in at least two different dosages. The present titration scheme/titration package may be useful in the treatment of various diseases, including tinnitus.

Inventors: Ellers-Lenz; Barbara (Morfelden-Walldorf, DE), Rosenberg; Tanja (Hamburg, DE), Seiller; Erhard (Nidderau, DE), Kruger; Hagen (Frankfurt am Main, DE), Althaus; Michael (Schoeneck, DE)

Assignee: Merz Pharma GmbH & Co. KGaA

International Classification: A61K 31/13 (20060101); A61P 27/16 (20060101); C07C 211/35 (20060101)

Expiration Date: 2019-11-04 0:00:00