Patent Number: 8,877,816

Title: 4-(or 5-) substituted catechol derivatives

Abstract: Compounds of the formula: ##STR00001## are disclosed. The compounds act as phosphodiesterase-4 modulators, and useful for treating stroke, myocardial infarct, and cardiovascular inflammatory conditions. Other embodiments are also disclosed.

Inventors: Singh; Jasbir (Naperville, IL), Gurney; Mark E. (Grand Rapids, MI), Burgin; Alex (Kingston, WA), Sandanayaka; Vincent (Northboro, MA), Kiselyov; Alexander (San Diego, CA)

Assignee: Decode Genetics EHF

International Classification: A61K 31/165 (20060101); C07C 233/02 (20060101); A61P 29/00 (20060101)

Expiration Date: 2019-11-04 0:00:00