Patent Number: 8,877,891

Title: Method of producing a novel opioid peptide

Abstract: The use of opioid peptides of a novel structure is claimed which, in addition to a pharmacophore, additionally contain structural elements reactive with tachykinin receptors. Due to the synergistic reactivity of the opioid with an additional element, an increased analgesic activity is obtained facilitating protracted effective use due to decreased drug tolerance effects. The drugs may particularly be of use in the treatment of chronic pain as effective analgesics during inflammation caused by rheumatism, gout, neurodegenerative states, post-surgical and post-traumatic inflammations or ones induced by tumors.

Inventors: Lipkowski; Andrej (Warsaw, PL)

Assignee:

International Classification: A61K 38/04 (20060101); C07K 5/107 (20060101); A61P 25/04 (20060101); A61K 38/07 (20060101); A61K 38/00 (20060101)

Expiration Date: 2019-11-04 0:00:00