Patent Number: 8,877,908

Title: Stimulus-responsive apta chelamers

Abstract: Disclosed are apta-chelamers comprising aptamer domains tethered to rationally designed synthetic protein-binding modules, and methods of designing and making the same. Also disclosed are stimulus-responsive apta-chelamers capable of simultaneously or sequentially binding (and, thus, inhibiting) two protein targets.

Inventors: Jayawickramarajah; Janarthanan (New Orleans, LA), Harris; David Calvin (Chicago, IL)

Assignee: The Administrators of the Tulane Educational Fund

International Classification: C07H 21/04 (20060101)

Expiration Date: 2019-11-04 0:00:00