Patent Number: 8,877,914

Title: Compositions comprising nucleic acids encoding HIV-1 reverse transcriptase CTL epitopes

Abstract: The present invention provides compositions comprising a vector including a nucleic acid comprising a nucleotide sequence encoding a peptide having the sequence X.sub.1LYQYMDDV, wherein X.sub.1 is any hydrophobic amino acid. The compositions are used to induce an immune response against human immunodeficiency virus (HIV).

Inventors: Berzofsky; Jay A. (Bethesda, MD), Okazaki; Takahiro (Yokohama, JP)

Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services

International Classification: C07H 21/04 (20060101); A61K 39/21 (20060101)

Expiration Date: 2019-11-04 0:00:00