Patent Number: 8,877,945

Title: Redox drug derivatives

Abstract: The present invention provides redox drug derivatives. In particular, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido- [1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinoline- carboxylic acid, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-car- boxylic acid ethyl ester, (3S)-3-(aminomethyl)-5-methylhexanoic acid, (3S)-1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-.alpha.-.alpha.-diphenyl-3-p- yrrolidineacetamide, (1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethyl-butyl]-4-(diaminomethylideneami- no)-2-hydroxy-cyclopentane-1-carboxylic acid and (2R,3R,4S)-4-[(diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-tri- hydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid redox derivatives.

Inventors: Lindsay; Derek (Liverpool, GB), Jackson; Peter (Liverpool, GB)

Assignee: Redx Pharma Limited

International Classification: C07D 401/10 (20060101); C07D 317/30 (20060101); C07D 209/48 (20060101); C07D 405/06 (20060101)

Expiration Date: 2019-11-04 0:00:00