Patent Number: 8,877,946

Title: Benzylidene-indolinone compounds and their medical use

Abstract: Compounds of general formula I: ##STR00001## wherein R.sup.1a, R.sup.1b, R.sup.2, R.sup.3a, R.sup.3b and X are as defined herein are tyrosine kinase inhibitors and are useful for the treatment of various diseases and conditions, for example cancer.

Inventors: Go; Mei Lin (Singapore, SG), Ho; Han Kiat (Singapore, SG), Chen; Xiao (Singapore, SG)

Assignee: National University of Singapore

International Classification: A61K 31/4015 (20060101); A61K 31/404 (20060101); C07D 209/34 (20060101)

Expiration Date: 2019-11-04 0:00:00