Patent Number: 9,801,832

Title: Pharmaceutical composition having synergistic action of direct catalase inhibitors and modulators of no metabolism or of extracellular superoxide anion production which lead to catalase destruction

Abstract: The present patent application relates to a pharmaceutical composition, characterized in that it comprises at least one active ingredient which can bring about a singlet oxygen-independent direct catalase inactivation and that the composition further comprises at least one active ingredient that leads to inactivation of catalase as a result of modulation of the nitrogen oxide or superoxide anion metabolism of the cells and subsequent singlet oxygen formation.

Inventors: Bauer; Georg (Freiburg, DE)

Assignee: Universitaetsklinikum Freiburg

International Classification: A61K 31/60 (20060101); A61K 31/375 (20060101); A61K 31/198 (20060101); A61K 31/26 (20060101); A61K 31/4164 (20060101); A61K 31/496 (20060101); A61K 31/05 (20060101); A61K 31/105 (20060101); A61K 31/337 (20060101); C07K 16/40 (20060101); A61K 31/352 (20060101); A61K 31/519 (20060101); A61K 31/69 (20060101); A61K 31/427 (20060101); A61K 31/426 (20060101); A61K 31/4196 (20060101); A61K 31/366 (20060101); A61K 31/10 (20060101)

Expiration Date: 2021-10-31 0:00:00