Patent Number: 9,809,569

Title: Process for producing heterocyclic compound

Abstract: The present invention provides a method of efficiently producing an optically active 6-(3-aminopiperidin-1-yl)-2,4-dioxo -1,2,3,4-tetrahydropyrimidine derivative. The optically active piperidine-3-carboxamide or a derivative thereof, which is obtained by subjecting 1,4,5,6-tetrahydropyridine -3-carboxamide or a derivative thereof to an asymmetric reduction in the presence of a catalyst, is used as an intermediate.

Inventors: Yamada; Masatoshi (Osaka, JP), Hirano; Sayuri (Osaka, JP), Tsuruoka; Ryoji (Osaka, JP), Yamano; Mitsuhisa (Osaka, JP)

Assignee: Takeda Pharmaceutical Company Limited

International Classification: C07D 401/04 (20060101); C07D 211/78 (20060101); C07D 211/60 (20060101); C07F 17/02 (20060101); C07F 9/50 (20060101); C07F 15/00 (20060101); B01J 31/22 (20060101); B01J 31/24 (20060101)

Expiration Date: 2022-11-07 0:00:00